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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 13.03
Human Site: S1048 Identified Species: 19.11
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S1048 I E D L K Y C S E H S V N E H
Chimpanzee Pan troglodytes XP_518055 1227 139177 S1041 I E D L K Y C S E H S V N E H
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S1048 I E D L K Y C S E H S V N E H
Dog Lupus familis XP_549061 1234 139874 S1050 I E D L K Y Y S E H S V N E P
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 L1046 Q S F A V G E L Q Y Y S E P S
Rat Rattus norvegicus Q7M6Z5 1394 158861 L1113 I A E I R A I L F K Y F N K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 P1029 S P F D Y I P P K P K T R R Q
Frog Xenopus laevis Q91784 1226 138905 K1044 G K R R T N A K S A A V I L E
Zebra Danio Brachydanio rerio Q58G59 1363 154819 E1141 E L E L R V E E Q Q N L V G W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 E602 A K Y D E E Q E E W K F S S M
Honey Bee Apis mellifera XP_395595 1064 123475 V878 E C M S K Q L V L N D T H S I
Nematode Worm Caenorhab. elegans P46873 699 78760 D517 G Y E R E I E D L H G E F E L
Sea Urchin Strong. purpuratus P46872 699 78679 E517 E S M R K M M E E R E Q E R M
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 Q864 G D A K N L L Q Y M F N S L G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 P996 S D H E R E D P D L D D E W K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 L746 F D V M K K S L M R D L Q N R
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 100 86.6 N.A. 0 13.3 N.A. N.A. 0 6.6 6.6 N.A. 6.6 6.6 13.3 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 13.3 40 N.A. N.A. 6.6 20 40 N.A. 26.6 20 26.6 13.3
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 0 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 13.3 N.A. N.A. 20 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 0 7 7 0 0 7 7 0 0 0 0 % A
% Cys: 0 7 0 0 0 0 19 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 25 13 0 0 7 7 7 0 19 7 0 0 0 % D
% Glu: 19 25 19 7 13 13 19 19 38 0 7 7 19 32 7 % E
% Phe: 7 0 13 0 0 0 0 0 7 0 7 13 7 0 0 % F
% Gly: 19 0 0 0 0 7 0 0 0 0 7 0 0 7 7 % G
% His: 0 0 7 0 0 0 0 0 0 32 0 0 7 0 19 % H
% Ile: 32 0 0 7 0 13 7 0 0 0 0 0 7 0 7 % I
% Lys: 0 13 0 7 44 7 0 7 7 7 13 0 0 7 7 % K
% Leu: 0 7 0 32 0 7 13 19 13 7 0 13 0 13 7 % L
% Met: 0 0 13 7 0 7 7 0 7 7 0 0 0 0 13 % M
% Asn: 0 0 0 0 7 7 0 0 0 7 7 7 32 7 0 % N
% Pro: 0 7 0 0 0 0 7 13 0 7 0 0 0 7 7 % P
% Gln: 7 0 0 0 0 7 7 7 13 7 0 7 7 0 7 % Q
% Arg: 0 0 7 19 19 0 0 0 0 13 0 0 7 13 7 % R
% Ser: 13 13 0 7 0 0 7 25 7 0 25 7 13 13 7 % S
% Thr: 0 0 0 0 7 0 0 0 0 0 0 13 0 0 0 % T
% Val: 0 0 7 0 7 7 0 7 0 0 0 32 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 7 % W
% Tyr: 0 7 7 0 7 25 7 0 7 7 13 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _